Bill Whitford of Arcadis Discusses 3D Printing for Biologics (INTERPHEX 2024)

At INTERPHEX, Invoice Whitford, Strategic Options chief at Arcadis, discusses the progress made in 3D bioprinting towards industrial biologics manufacturing.

Pharmaceutical Know-how® speaks to Invoice Whitford, Strategic Options chief at Arcadis, on the position and affect of 3D bioprinting for biologics. Whitford is a presenter on the subject of 3D bioprinting at INTERPHEX, held in New York Metropolis on April 16–18.

Whitford notes that an necessary facet of 3D bioprinting is that it’s one strategy to 3D cell tradition, which he observes is taking up cell tradition in lots of classes. “3D tradition supplies many distinctive capabilities it is extra biomimetic. Truly, there’s nothing pure about rising cells in monolayer on a styrene plate, so there are various 3D tradition applied sciences that make use of many alternative manufacturing strategies that assist many classes of utility and particular person merchandise,” Whitford states.

On the workflow in a 3D bioprinting facility, Whitford remarks that many complementary and supportive synergistic applied sciences exist that assist one another. “For instance,” he explains, “machine imaginative and prescient now could be actually easy. Ordering 3D printing and the power to each direct and examine a nascent print job utilizing synthetic intelligence (AI) … they feed on one another. The supply of bioprinters and what we name bio ‘inks’ is, in a industrial sense, what’s actually driving the ultimate purposes.”

“Finest practices are being developed for bioprinting,” Whitford additionally notes, mentioning that there are various other ways of affecting bioprinting, not simply with respect to the instrumentation, however with respect to the precise printing. “There may be laser-effected printing; there’s extrusion-effected printing. There are various other ways of getting the bio ink into the three-dimensional construction, they usually all have their benefits. All of them present both an amazing accuracy and precision or quantity.”

Within the interview, Whitford additionally discusses the way forward for 3D bioprinting within the cell and gene remedy sector. “The flexibility now—by way of site-directed CRISPR [clustered regularly interspaced short palindromic repeats]-type engineering—to drive the evolution of a cell in the direction of precisely what phenotype is required is supporting the power to … develop the bio ink … required to get the preliminary print job achieved.”

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